Suppression of Matrix Metallopeptidase-3 Expression in Human Dermal Fibroblasts by Decursin from Angelica gigas Nakai Root Extracts Fermented with Jeju Lava Seawater
نویسندگان
چکیده
목ì ìµ?본 ì?°êµ¬ë?? ì ?주 ì?©ì??í?´ì??ë¡? ì??ì?±ë? ì°¸ë?¹ê·? ì¶?ì¶?물ì? ì¸ê°? ì§?í?¼ì?¬ì? ì??ì?¸í¬ ë?´ ì½?ë¼ê²ë¶?í?´í?¨ì?? ë°?í?? ê°ì?? í?¨ê³¼ë¥¼ ë¶?ì?í??ê³ ê·¸ í?¨ê³¼ì? ë??í?? ì§?í??물ì§?ì? í??ì? í??ë?? ê²?ì? ì?¼ë¡? ì§?í??ë?ì??ë?¤. ë°©ë²? ì?©ì??í?´ì??를 ì´ì?©í?´ ?ì?¨ì??ì?±í??ì?¬ ì¶?ì¶?í?? ì§?í??물ì§? í??ì¸ì? ì??í?´ ê³ ì?±ë?¥ ì?¡ì²´ í¬ë¡?ë§?í? ê·¸ë??í?¼(HPLC) ë¶?ì?ì? ì§?í??í??ì??ë?¤. ë¿?리 ì¶?ì¶?물 ë° decursinì? ì?¸í¬ì?ì¡´ì?¨ì? 측ì ?í??ê³ ì?¤ì??ê°? ì? ?ì?ì¦í ?ë??(qRT-PCR) í?µí?? ë³?í??를 ë¶?ì?í??ì??ë?¤. Decursinì?¼ë¡? ì§?í??í?? ê²°ê³¼ì?? ë¹?êµí??ì?¬ ì?ê´?ê´?ê³?를 í??ì??ë?¤. ê²°ê³¼ HPLC ë¶?ì? ê²°ê³¼, 주ì??í?? ì§?í??물ì§?ë¡? decursinì´ í??ì¸ë?ì??ë?¤. ì??ì?¸í¬ì?ì?? ì¶?ì¶?물과 decursinì? ê°ê° 200 μg/mL, 20 μM 미ë§?ì? ë?ë?ì?ì?? ì?¸í¬ ì?ì¡´ì?¨ì? ë?®ì? ì?í?¥ì? ë³´ì??ë?¤. ë?í??, MMP3 ë°?í??ì? qRT-PCRì? í?µí?´ í??ì¸í??ì??ë?¤. ê²°ë¡ ë³¸ ì?°êµ¬ê²°ê³¼ë¥¼ ì´ ì¶?ì¶?물ë¡?ë¶?í?° ì??ì??ë¶?리ë? ì½?ë¼ê²ë¶?í?´í?¨ì??ì¸ í?¨ë?¥ì? í??ì¸í??ì??ì?¼ë©°, ì´ë¥¼ decursionì? 주ë¦?ê°?ì? ì?© 기ë?¥ì?±í??ì?¥í?? ì??ì?¬ë¡? í??ì?© ê°?ë?¥í?¨ì? ê³¼í??ì ì¦ëª í?µì?¬ì?©ì?´: ë¿?리, Decursin, ì½?ë¼ê²ë¶?í?´í?¨ì??, ì?©ì??í?´ì??,
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ژورنال
عنوان ژورنال: Asian Journal of Beauty and Cosmetology
سال: 2021
ISSN: ['2466-2046', '2466-2054']
DOI: https://doi.org/10.20402/ajbc.2020.0120